Eduard H Panosyan Selected Research

Asparagine

1/2018	Efficacy of Asparaginase Erwinia chrysanthemi With and Without Temozolomide Against Glioma Cells and Intracranial Mouse Medulloblastoma.
1/2017	In search of druggable targets for GBM amino acid metabolism.
1/2016	Clinical aggressiveness of malignant gliomas is linked to augmented metabolism of amino acids.
5/2014	Asparagine depletion potentiates the cytotoxic effect of chemotherapy against brain tumors.
8/2004	Asparaginase pharmacokinetics after intensive polyethylene glycol-conjugated L-asparaginase therapy for children with relapsed acute lymphoblastic leukemia.
3/2004	Changes of amino acid serum levels in pediatric patients with higher-risk acute lymphoblastic leukemia (CCG-1961).

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Eduard H Panosyan Research Topics

Disease

7	Neoplasms (Cancer) 04/2022 - 04/2004
6	Brain Neoplasms (Brain Tumor) 04/2022 - 01/2011
5	Glioma (Gliomas) 01/2018 - 05/2013
5	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 12/2015 - 03/2004
4	Medulloblastoma 04/2022 - 01/2017
2	Sickle Cell Anemia (Hemoglobin S Disease) 07/2022 - 07/2018
2	Glioblastoma (Glioblastoma Multiforme) 01/2017 - 05/2014
2	Hypersensitivity (Allergy) 12/2015 - 04/2004
2	Leukemia 05/2014 - 03/2004
1	Melanoma (Melanoma, Malignant) 01/2019
1	Body Weight (Weight, Body) 07/2018
1	Chest Pain (Chest Pains) 07/2018
1	Fatigue 07/2018
1	Nausea 07/2018
1	Pain (Aches) 07/2018
1	Musculoskeletal Pain 07/2018
1	Weight Loss (Weight Reduction) 01/2018
1	Infections 05/2015
1	Necrosis 05/2015
1	Residual Neoplasm 05/2013
1	Lymphoma (Lymphomas) 01/2005

Drug/Important Bio-Agent (IBA)

6	AsparagineIBA 01/2018 - 03/2004
6	Asparaginase (Elspar)FDA Link 01/2018 - 03/2004
5	Glutamine (L-Glutamine)FDA Link 07/2022 - 03/2004
4	Temozolomide (Temodar)FDA LinkGeneric 01/2019 - 05/2014
4	Amino Acids FDA Link 01/2017 - 03/2004
3	EnzymesIBA 01/2017 - 05/2014
2	Hydroxyurea (Hydrea)FDA LinkGeneric 07/2022 - 07/2018
2	Biological ProductsIBA 04/2022 - 05/2014
2	Gemcitabine FDA Link 04/2022 - 05/2014
2	Aspartate-Ammonia Ligase (Asparagine Synthetase)IBA 01/2016 - 05/2014
2	AntibodiesIBA 12/2015 - 08/2004
1	Sirolimus (Rapamycin)FDA Link 04/2022
1	humaninIBA 01/2019
1	Niacinamide (Nicotinamide)FDA LinkGeneric 07/2018
1	Adenine FDA LinkGeneric 07/2018
1	Pharmaceutical PreparationsIBA 07/2018
1	DNA (Deoxyribonucleic Acid)IBA 01/2018
1	Tryptophan (L-Tryptophan)FDA Link 01/2017
1	DioxygenasesIBA 01/2017
1	gamma-Aminobutyric Acid (GABA)IBA 01/2017
1	Arginine (L-Arginine)FDA Link 01/2017
1	glutamate decarboxylase 1IBA 01/2017
1	Proteins (Proteins, Gene)FDA Link 01/2017
1	Transaminases (Aminotransferases)IBA 01/2017
1	Proline Oxidase (Proline Dehydrogenase)IBA 01/2017
1	GlutaminaseIBA 01/2016
1	Branched-Chain Amino AcidsIBA 01/2016
1	Diff QuikIBA 05/2015
1	Messenger RNA (mRNA)IBA 05/2014
1	Etoposide (VP 16)FDA LinkGeneric 05/2014
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2006
1	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 08/2004

Therapy/Procedure

8	Therapeutics 07/2022 - 08/2004
5	Drug Therapy (Chemotherapy) 04/2022 - 01/2011
2	Immunotherapy 04/2022 - 05/2013
1	Biological Therapy 04/2022
1	Combination Drug Therapy (Combination Chemotherapy) 08/2004